Insights for Data-Driven Decisions
The Percepta Platform is a portfolio of software applications and a technology ecosystem for predicting and managing physicochemical, ADME/Tox, and other molecular property data.
With Percepta applications you can predict molecular properties from structure, and train models with experimental data. You can even include custom models created in-house to centrally manage in silico calculations and training sets for distribution so that everyone calculating property data is using up-to-date information.
Software on the Percepta Platform Is Right for You If…
- Your goal is to facilitate the discovery and optimization of novel compounds with prescribed drug-like/real-world properties
- You want to reduce the cost of R&D by helping scientists evaluate the behavior and performance of compounds before assay or synthesis
- Your organization would benefit from in silico molecular property data being stored, updated, and managed in one place for distribution to those that need it
- You’re searching for a high-throughput screening platform to support early research or create complete compound profiles
- In silico data is an acceptable alternative to experimental data in some of your regulatory documents/submissions
The Percepta Difference
Industry-Leading Models
- Our models and algorithms have been part of the portfolio of in silico calculators used by major pharma and environmental researchers for more than 25 years
- Training databases of Percepta calculation models are based on carefully curated experimental data that provide fast, accurate, and reliable results
- Gauge the reliability of results yourself from calculation protocols, provided reliability index, a display of similar structures in the database, and literature references for experimental data
Easy to Use
- Draw or import a structure to calculate properties. The software makes it easy for everyone to generate results and understand them.
- Model training can be done by anyone—you don’t need experience in computational chemistry or programming
Insights from Data
- Visualize the substructure/atomic contributions to a property value with color-mapping on the structure (feature available in some prediction modules)
- Identify trends and prioritize compounds with tools to plot, filter, sort, and rank
Trainable Algorithms
- Get the accuracy of proprietary models from a commercial product. Use the experimental data collected in-house to enhance the accuracy of prediction models for novel chemical space.
Expandable to Third-Party Models
- Consolidate all your existing property calculators in one place—models created by your own teams and third-party algorithms
Flexible Deployment Options
- Percepta software can be installed on individual computers or deployed as a browser-based application
- Use batch deployment for high-throughput screening
Integrate with Pipeline Pilot & KNIME
- Percepta calculators may be incorporated into workflow tools such as Pipeline Pilot
- KNIME integration components are available for thin client deployments
Predictive Modules in Percepta
Physicochemical
- Aqueous Solubility
- Boiling Point/Vapor Pressure
- LogD
- LogP
- pKa
- Sigma
ADME
- Blood Brain Barrier Permeation
- Cytochrome P450 Inhibitors
- Cytochrome P450 Substrates
- Distribution
- Maximum Recommended Daily Dose
- Oral Bioavailability
- Passive Absorption
- P-gp Specificity
- PK Explorer
- Regioselectivity of Metabolism
Toxicity
- Acute Toxicity
- Aquatic Toxicity
- Endocrine System Disruption
- Mutagenicity
- Health Effects
- hERG Inhibition
- Irritation
Customer Reviews
>80%
Of the world's top 25 pharma companies choose Percepta prediction tools from ACD/Labs
>1100
Companies and institutions around the world choose Percepta for molecular profiling and property prediction
> 90%
Of our clients choose to continue using our software year after year
> 4,600
R&D sites worldwide choose ACD/Labs software