ACD/Labs Blog

Chloraserrtone A, a new sesquiterpenoid dimer with two lindenane-type sesquiterpenoid monomers bridged by two six-membered rings, was isolated from Chloranthus serratus by Bai et al. It represents the first lindenane-type sesquiterpenoid dimer with an extremely unique skeleton, molecular formula C₃H₃₆O₉.

The Penicillium sp. KFS28 fungus was isolated from a bivalve mollusk, Meretrix Lusoria, from the Haikou Bay in China. The EtOAc extract of the fermentation broth was processed by the authors who isolated and identified four new paxilline-type indole-terpenoids. Compound 1 has the molecular formula C₂₈H₃₅NO₆.

Goudou at al described the isolation of a novel metabolite, orbicularisine, from the tropical bivalve Codakia orbicularis living in seagrass beds, molecular formula C₁₃H₁₀N₂O₅S.

Feng et al investigated the chemical constituents of N. tabacum leaves by a dereplication procedure, which resulted in the isolation of a novel compound, nicotabin A, molecular formula C₂₁H₂₈O₇.

Gao et al isolated, amongst others, Cascarinoid A, the first example of a crotofolane diterpenoid alkaloid, molecular formula C₂₈H₃₁NO₅.

Zhao and coworkers had been studying the secondary metabolites of Biscogniauxia sp. They isolated a diisoprenyl-cyclohexane-type meroterpenoid dimer with a new skeleton, Dimericbiscognienyne A (molecular formula C₃₂H₄₀O₆).

Yaouba et al reported the isolation and phytochemical investigation of the constituents of Aspilia pluriseta Schweinf and Aspilia mossambicensis. They isolated, identified and comprehensively investigated compound 1, molecular formula C₂₁H₃₀O₃.

El-Elimat et al reported five new and one known meroterpenoids, including the discovery of a novel ioxa[4.3.3]propellane metabolite neosetophomone A that incorporates a 3-methyl-2,3-dihydrofuran bridge into a 5,6 tricyclic 2-hydroxycyclopent-2-en-1-one/tetrahydropyran ring system, molecular formula C₂₄H₃₂O₅.

Zhou et al isolated three novel diterpenoids with an unprecedented 2,3:5,6-di-seco-grayanane carbon skeleton. Rhodomollacetal A was obtained as colorless prisms, molecular formula C₂₁H₃₂O₇.

As a part of an ongoing research for SNTs from Schisandra micrantha, a minor SNT featuring a complex tetracyclo[5.4.0.02,4.03,7]undecane-bridged system, termed lancolide E, was isolated by Shi et al, molecular formula C₂₉H₃₂O₁₀.