An Assessment of the Ocular Toxicity of Two Major Sources of Environmental Exposure

This article focuses on the effect of airborne exposure on the eye surface, particularly in light of the increasing number of incidents occurring in both civilian and military settings. In this study, in silico methods based on a platform comprising a portfolio of software applications (including ACD/Labs ADME Suite and Tox Suite) and a technology ecosystem are used to test potential surface ocular toxicity in data presented from Iraqi burn pits and the East Palestine, Ohio, train derailment. The purpose of this analysis is to gain a better understanding of the long-term impact of such an exposure to the ocular surface and the manifestation of surface irritation, including dry eye disease.